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SCSouth Carolina rankings

Towns with the lowest depression rates in South Carolina

Ranked by the share of adults who have ever been told by a doctor that they have depression, as estimated by the CDC. 173 towns with 2,500+ residents.

CDC PLACES health estimates, 2025 release

Central
South Carolina · Lowest depression

Where Central lands: #162 of 173

27% of adults have been diagnosed with depression · Visit Central →

Hilton Head Island 1 Hilton Head Island 17% Likely range 15–19% McCormick 2 McCormick 18% Likely range 15–21% 3 Keowee Key 19% Likely range 16–22%
#TownAdults with depressionLikely rangePopulation
1 Hilton Head Island Hilton Head Island37,911 people 17% 15–19% 37,911
2 McCormick McCormick2,506 people 18% 15–21% 2,506
T3 Keowee Key3,351 people 19% 16–22% 3,351
T3 Litchfield Beach Litchfield Beach9,044 people 19% 16–22% 9,044
T3 Bluffton Bluffton33,157 people 19% 17–22% 33,157
T3 Isle of Palms Isle of Palms4,362 people 19% 17–22% 4,362
T7 Map of Hollywood Hollywood5,382 people 20% 17–22% 5,382
T7 North Myrtle Beach North Myrtle Beach19,855 people 20% 17–22% 19,855
T7 Map of Burton Burton6,912 people 20% 17–22% 6,912
T7 Ridgeland Ridgeland3,764 people 20% 17–23% 3,764
T7 Map of Allendale Allendale2,653 people 20% 16–23% 2,653
T7 Ravenel Ravenel2,615 people 20% 17–22% 2,615
T7 Beaufort Beaufort13,747 people 20% 17–22% 13,747
T7 Map of Georgetown Georgetown8,565 people 20% 17–23% 8,565
T7 Denmark Denmark3,117 people 20% 17–23% 3,117
T7 Murrells Inlet Murrells Inlet10,044 people 20% 17–23% 10,044
T7 Kingstree Kingstree3,132 people 20% 17–23% 3,132
T7 Map of Port Royal Port Royal15,579 people 20% 18–23% 15,579
T7 Mullins Mullins3,914 people 20% 17–24% 3,914
T7 Andrews Andrews3,485 people 20% 18–24% 3,485
T7 Saluda Saluda3,055 people 20% 17–24% 3,055
T22 Five Forks18,656 people 21% 18–23% 18,656
T22 Hardeeville Hardeeville10,871 people 21% 17–24% 10,871
T22 Map of Gantt Gantt15,401 people 21% 18–23% 15,401
T22 Map of Tega Cay Tega Cay13,615 people 21% 18–23% 13,615
T22 Map of Little River Little River11,771 people 21% 18–23% 11,771
T22 Map of Loris Loris2,645 people 21% 18–23% 2,645
T22 Lake City Lake City5,988 people 21% 18–24% 5,988
T22 Bamberg Bamberg2,996 people 21% 18–24% 2,996
T22 Map of Garden City Garden City11,591 people 21% 18–23% 11,591
T22 Map of Brookdale Brookdale4,291 people 21% 18–24% 4,291
T22 James Island James Island12,198 people 21% 18–24% 12,198
T22 Bennettsville Bennettsville7,751 people 21% 18–24% 7,751
T22 Surfside Beach4,270 people 21% 19–24% 4,270
T22 Map of Cherryvale Cherryvale2,611 people 21% 18–24% 2,611
T22 Sumter Sumter43,053 people 21% 18–24% 43,053
T22 Map of Woodfield Woodfield9,465 people 21% 19–24% 9,465
T22 Varnville2,571 people 21% 18–25% 2,571
T22 Map of Dentsville Dentsville15,209 people 21% 19–24% 15,209
T22 Mauldin Mauldin27,055 people 21% 19–24% 27,055
T22 Map of Mount Pleasant Mount Pleasant93,993 people 21% 19–24% 93,993
T22 Wade Hampton20,898 people 21% 19–24% 20,898
T22 Orangeburg Orangeburg13,253 people 21% 18–25% 13,253
T22 Camden Camden8,267 people 21% 18–25% 8,267
T22 Judson2,515 people 21% 19–24% 2,515
T46 North Charleston North Charleston119,913 people 22% 19–24% 119,913
T46 Aiken Aiken32,521 people 22% 19–24% 32,521
T46 Marion Marion6,206 people 22% 18–25% 6,206
T46 Map of India Hook India Hook3,960 people 22% 19–24% 3,960
T46 Myrtle Beach Myrtle Beach38,371 people 22% 19–24% 38,371
T46 East Camden4,194 people 22% 19–25% 4,194
T46 Bishopville Bishopville2,910 people 22% 18–25% 2,910
T46 Map of Forestbrook Forestbrook7,479 people 22% 19–24% 7,479
T46 Welcome6,527 people 22% 19–24% 6,527
T46 Cheraw Cheraw4,960 people 22% 19–25% 4,960
T46 Hampton Hampton2,636 people 22% 19–25% 2,636
T46 Simpsonville Simpsonville26,144 people 22% 19–25% 26,144
T46 Map of Taylors Taylors24,505 people 22% 19–25% 24,505
T46 Darlington Darlington6,120 people 22% 19–25% 6,120
T46 Dalzell2,946 people 22% 19–25% 2,946
T46 Homewood2,708 people 22% 19–24% 2,708
T46 Map of Blythewood Blythewood5,731 people 22% 19–25% 5,731
T46 Walterboro Walterboro5,480 people 22% 19–25% 5,480
T46 Edgefield Edgefield4,010 people 22% 19–25% 4,010
T46 Fort Mill Fort Mill30,775 people 22% 20–25% 30,775
T46 Barnwell Barnwell4,613 people 22% 19–25% 4,613
T46 Map of Newport Newport4,121 people 22% 19–25% 4,121
T46 Abbeville Abbeville4,872 people 22% 19–26% 4,872
T46 Map of Williston Williston2,870 people 22% 19–25% 2,870
T46 Rock Hill Rock Hill75,259 people 22% 20–25% 75,259
T46 Laurens Laurens9,336 people 22% 19–25% 9,336
T46 Florence Florence40,408 people 22% 19–26% 40,408
T46 Lake Wylie Lake Wylie16,006 people 22% 20–25% 16,006
T46 Map of Red Hill Red Hill15,920 people 22% 20–25% 15,920
T46 Chester Chester5,218 people 22% 19–26% 5,218
T46 Manning Manning3,863 people 22% 19–26% 3,863
T46 Greenville Greenville72,935 people 22% 20–25% 72,935
T46 Carolina Forest26,263 people 22% 20–25% 26,263
T46 Gaffney Gaffney12,596 people 22% 19–26% 12,596
T46 Map of Laurel Bay Laurel Bay5,882 people 22% 20–26% 5,882
T81 Socastee Socastee23,796 people 23% 20–25% 23,796
T81 Map of Berea Berea16,862 people 23% 20–25% 16,862
T81 Fountain Inn Fountain Inn12,020 people 23% 20–25% 12,020
T81 Wyboo3,639 people 23% 19–26% 3,639
T81 Hilltop2,950 people 23% 20–26% 2,950
T81 Charleston Charleston154,338 people 23% 20–25% 154,338
T81 Greer Greer41,536 people 23% 20–25% 41,536
T81 Map of Ladson Ladson16,140 people 23% 20–26% 16,140
T81 Newberry Newberry10,790 people 23% 19–26% 10,790
T81 Lugoff9,786 people 23% 19–26% 9,786
T81 Dillon Dillon6,354 people 23% 19–26% 6,354
T81 Map of New Ellenton New Ellenton2,837 people 23% 20–25% 2,837
T81 Forest Acres Forest Acres10,530 people 23% 20–26% 10,530
T81 Summerville Summerville51,654 people 23% 20–26% 51,654
T81 Goose Creek Goose Creek48,078 people 23% 20–26% 48,078
T81 Seven Oaks Seven Oaks15,921 people 23% 20–26% 15,921
T81 Irmo Irmo11,813 people 23% 21–25% 11,813
T81 York York8,969 people 23% 20–26% 8,969
T81 Winnsboro Winnsboro3,322 people 23% 20–26% 3,322
T81 North Augusta North Augusta25,653 people 23% 20–26% 25,653
T81 Moncks Corner Moncks Corner15,485 people 23% 20–26% 15,485
T81 Baxter Village4,542 people 23% 20–26% 4,542
T81 Capitol View4,374 people 23% 20–26% 4,374
T81 Dunean3,668 people 23% 20–26% 3,668
T81 Arkwright2,816 people 23% 20–26% 2,816
T81 St. Andrews St. Andrews19,868 people 23% 20–26% 19,868
T81 Map of Union Union8,079 people 23% 20–27% 8,079
T81 Sans Souci7,665 people 23% 20–26% 7,665
T81 Map of Lake Murray of Richland Lake Murray of Richland7,023 people 23% 20–26% 7,023
T81 Hanahan21,452 people 23% 20–27% 21,452
T81 Lancaster Lancaster8,921 people 23% 20–26% 8,921
T81 Batesburg-Leesville Batesburg-Leesville4,941 people 23% 21–26% 4,941
T81 Lakewood3,544 people 23% 20–27% 3,544
T81 Clinton Clinton7,676 people 23% 20–27% 7,676
T81 Map of Lesslie Lesslie3,077 people 23% 21–26% 3,077
T116 Map of North Hartsville North Hartsville3,304 people 24% 20–27% 3,304
T116 Spartanburg Spartanburg38,910 people 24% 21–27% 38,910
T116 Lexington Lexington24,585 people 24% 21–27% 24,585
T116 Map of Golden Grove Golden Grove2,913 people 24% 21–27% 2,913
T116 Hartsville Hartsville7,419 people 24% 21–27% 7,419
T116 Map of Belvedere Belvedere5,180 people 24% 21–27% 5,180
T116 Whitney3,685 people 24% 21–27% 3,685
T116 Greenwood Greenwood22,536 people 24% 21–27% 22,536
T116 Map of Boiling Springs Boiling Springs12,936 people 24% 21–27% 12,936
T116 Parker12,898 people 24% 21–27% 12,898
T116 Conway Conway27,263 people 24% 21–27% 27,263
T116 Easley24,841 people 24% 21–28% 24,841
T116 West Columbia West Columbia17,963 people 24% 21–27% 17,963
T116 Map of Wellford Wellford3,515 people 24% 21–27% 3,515
T116 Arcadia3,426 people 24% 21–27% 3,426
T116 Map of Roebuck Roebuck2,902 people 24% 21–27% 2,902
T116 Sangaree8,681 people 24% 21–28% 8,681
T116 Clover Clover7,234 people 24% 22–27% 7,234
T116 Pickens Pickens3,155 people 24% 21–28% 3,155
T116 Woodruff Woodruff4,538 people 24% 22–28% 4,538
T136 Map of Clearwater Clearwater3,319 people 25% 22–28% 3,319
T136 Powdersville10,771 people 25% 22–28% 10,771
T136 Seneca Seneca8,993 people 25% 22–29% 8,993
T136 Map of Northlake Northlake4,390 people 25% 22–28% 4,390
T136 Duncan Duncan4,310 people 25% 22–28% 4,310
T136 Map of Gloverville Gloverville2,505 people 25% 22–28% 2,505
T136 Oak Grove Oak Grove12,256 people 25% 22–28% 12,256
T136 Map of Travelers Rest Travelers Rest8,370 people 25% 22–28% 8,370
T136 Southern Shops3,797 people 25% 22–28% 3,797
T136 Columbia Columbia139,643 people 25% 22–28% 139,643
T136 Liberty Liberty3,350 people 25% 22–29% 3,350
T136 Inman Inman3,166 people 25% 22–28% 3,166
T136 Map of Ninety Six Ninety Six2,521 people 25% 22–29% 2,521
T136 Burnettown Burnettown3,135 people 25% 23–28% 3,135
T136 Springdale Springdale2,742 people 25% 22–28% 2,742
T136 Map of Lyman Lyman6,547 people 25% 23–29% 6,547
T136 Landrum Landrum2,620 people 25% 22–29% 2,620
T153 Map of Centerville Centerville7,049 people 26% 22–29% 7,049
T153 Anderson Anderson30,051 people 26% 23–29% 30,051
T153 Cayce Cayce13,741 people 26% 23–29% 13,741
T153 Pendleton Pendleton3,594 people 26% 23–29% 3,594
T153 Pine Ridge Pine Ridge2,596 people 26% 23–29% 2,596
T153 Map of East Gaffney East Gaffney2,824 people 26% 22–30% 2,824
T153 Map of Saxon Saxon4,085 people 26% 23–30% 4,085
T153 Map of Valley Falls Valley Falls8,239 people 26% 23–29% 8,239
T153 Walhalla Walhalla4,157 people 26% 23–30% 4,157
T162 Map of Piedmont Piedmont5,462 people 27% 24–29% 5,462
T162 Map of Honea Path Honea Path3,739 people 27% 24–30% 3,739
T162 White Knoll White Knoll8,310 people 27% 24–30% 8,310
T162 Map of Clemson Clemson18,072 people 27% 24–31% 18,072
T162 Red Bank Red Bank11,314 people 27% 24–30% 11,314
T162 Belton Belton4,458 people 27% 24–31% 4,458
T162 Westminster Westminster2,521 people 27% 24–31% 2,521
T162 Central Central5,320 people 27% 24–31% 5,320
T162 Williamston Williamston4,170 people 27% 24–31% 4,170
171 Map of Homeland Park Homeland Park6,632 people 28% 25–31% 6,632
172 Arthurtown3,272 people 29% 26–33% 3,272
173 Clemson University7,015 people 32% 28–37% 7,015

How this ranking works

We rank every town by the share of adults who have ever been told by a doctor that they have depression, as estimated by the CDC. The lowest share ranks #1. Across South Carolina it’s 22%.

These are the CDC’s modeled estimates, not a count: national survey answers combined with each area’s age, sex, race and income mix. Each carries a likely range (shown in the table), so we rank on the whole percent and towns at the same figure share a rank (T = tied). Differences of a point or two are within the estimates’ margins.

Cities and villages use the CDC’s own estimate for that place. New England towns and townships, which the CDC doesn’t publish, use the ZIP codes that cover them, weighted by land area.

Only towns with at least 2,500 residents are ranked; Census estimates for smaller places are too uncertain. Population and income: U.S. Census Bureau American Community Survey 5-year estimates. Health estimates: CDC PLACES. Town photos: Wikimedia Commons, credited on each town’s page.

Same ranking in other states

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