Mayesville is a town in Sumter County, South Carolina, United States. The population was 731 at the 2010 census, this was a decline from 1,001 in 2000. It is included in the Sumter, South Carolina Metropolitan Statistical Area.

Official town website ↗

From Wikipedia, licensed CC BY-SA 4.0 · facts via Wikidata (CC0)

Town numbers

ZIP code29104

Area code803

Living in Mayesville

Housing in Mayesville

$92K▼ 12.3% in a year Typical home value · Zillow

The typical Mayesville home is worth about $92,000, down 12.3% in a year, 70% below the South Carolina typical home.

Zillow Home Value Index · Redfin Data CenterHousing market →

Work & commute in Mayesville

Full picture →

Most working residents leave Mayesville for work: only 1% work in town. The top destinations are Sumter (32%), Columbia (7%) and Camden (2%). Half commute less than 13 miles.

Sumter

32%

Columbia

Camden

Charlotte, NC

1%Work in townlive and work in Mayesville 13 miWhere do people commute?the commute map 28Jobs based herea commuter town

Census LEHD 2023 · ACSWork & commute in Mayesville →

Health in Mayesville

Compared with South Carolina

5better than SC·20worse

of 32 measures CDC estimates. The other 7 are too close to call.

Conditions 2▲ 9▼ 1 close Habits 1▲ 3▼ 0 close Care 2▲ 1▼ 4 close Mind 3▼ 2 close Everyday needs 4▼ 0 close

BetterToo close to callWorse

What stands out

10.5%Fewer binge drinkersSC 15.7% · better 6.9%Fewer adults who have had cancerSC 8.6% · better 16.5%More adults facing a utility shut-offSC 8.9% · worse

Care nearby

Prisma Health Tuomey HospitalSumter · 9.1 mi · ER

Tandem HealthSumter · 7.6 mi · sliding-scale fees

Primary careShortage · county-wide

DentalShortage · county-wide

Mental healthShortage · county-wide

CDC PLACES 2025 · modeled estimates for adults · CDC's estimate for Mayesville · CMS · HRSAHealth in Mayesville →

Natural hazards in Mayesville

Moderate

Expected storm and flood damage is higher than in 47% of U.S. communities.

🌊 Inland flooding🌀 Hurricanes🏚️ Earthquakes

0Does Mayesville flood?no paid flood claims on record 3Disasters that paid out herefederal disasters sent FEMA money to Mayesville

FEMA National Risk Index December 2025 · OpenFEMANatural hazards in Mayesville →

Climate in Mayesville

Full climate →

Mayesville has mild winters and warm summers, with plenty of rain. A typical July afternoon reaches 92°, a January night drops to 34°, and snow is almost unheard of.

59° / 36°Winter

76° / 50°Spring

90° / 69°Summer

76° / 53°Fall

How much snow does Mayesville get?Almost none.Rain & snow →When is the first frost?Around Nov 7, with the last in spring around Mar 24.Frost dates →Is it warmer than it used to be?+0.8° vs. the 20th century.Then & now →

NOAA U.S. Climate Normals, 1991–2020Climate in Mayesville →