Howard Ehmke
1894–1959 American baseball player
Alice Lee Jemison
1901–1964 Seneca political activist and journalist
G. Peter Jemison
born 1945 Seneca painter and sculptor
George Borrello
born 1967 American politician and businessman
Jeff Wise
born 1953 American metalworker
Joseph J. Villafranca
born 1944 American biochemist and executive
Robert J. Genco
1938–2019 American periodontist and microbiologist