Depew () is a village in Erie County, New York. As of the 2020 census, Depew had a population of 15,178. It is part of the Buffalo–Niagara Falls metropolitan area. The village is named for Chauncey Depew, a politician and one of the original investors who bought the land for the village, which was incorporated in 1894. The village extends across the boundary between the towns of Lancaster and Cheektowaga. The village lies on both sides of NY Route 78 (Transit Road), a major north-south route. Village residents voted on January 17, 2017, to not dissolve the Village of Depew into the Towns of Lancaster and Cheektowaga, by a margin of 3,006–1,165.

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How Depew ranks

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#104Shortest commute in NY #115Fewest uninsured in NY #146Most walkable in NY All NY rankings →

Town numbers

ZIP code14043

Area codeSign in to add

Living in Depew

Housing in Depew

$273K▲ 3.7% in a year Typical home value · Zillow

The typical Depew home is worth about $273,000, up 3.7% in a year, 48% below the New York typical home.

A seller's market

Buyer’sBalancedSeller’s

Days on market9

Sale-to-list114.2%

Sold in May10

Zillow Home Value Index · Redfin Data CenterHousing market →

Safety in Depew

B⁻

Safety Grade B-

Depew reports more crime per resident than most U.S. towns we grade: about 51% report less.

Violent crime per 1,000

Depew 0.9

New York 3.7

U.S. 3.3

Property crime per 1,000

Depew 13.6

New York 15.7

U.S. 15.5

FBI crime data, 2025 · crimes reported to policeCrime & safety →

Work & commute in Depew

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Most working residents leave Depew for work: only 8% work in town. The top destinations are Buffalo (21%), Amherst (16%) and Cheektowaga (14%). Half commute less than 8 miles.

Buffalo

21%

Amherst

16%

Cheektowaga

14%

Lancaster

13%

8%Work in townlive and work in Depew 8 miWhere do people commute?the commute map 8,669Jobs based herebalanced

Census LEHD 2023 · ACSWork & commute in Depew →

Health in Depew

B⁺

Health Grade B+

Healthier than 74% of U.S. towns on seven CDC estimates, and 89% of towns with similar incomes.

Compared with New York

8better than NY·3worse

of 32 measures CDC estimates. The other 21 are too close to call.

Conditions 1▲ 3▼ 8 close Habits all close Care 2▲ 5 close Mind 1▲ 4 close Everyday needs 4▲ 0 close

BetterToo close to callWorse

What stands out

11.2%Fewer adults facing food insecurityNY 17.2% · better 5.4%Fewer uninsured adultsNY 7.9% · better 21.8%More adults with depressionNY 17.5% · worse

Care nearby

Upstate New York VA Healthcare System (Western Ny VA Healthcare System)Buffalo · 6.2 mi · ER

Evergreen Health - Community Dr.Cheektowaga · 3.8 mi · sliding-scale fees

Primary careNo shortage

DentalNo shortage

Mental healthNo shortage

CDC PLACES 2025 · modeled estimates for adults · CDC's estimate for Depew · CMS · HRSAHealth in Depew →

Natural hazards in Depew

Low

Expected storm and flood damage is higher than in 29% of U.S. communities.

🌊 Inland flooding🥶 Cold waves

21Does Depew flood?paid flood claims since 1978 7Disasters that paid out herefederal disasters sent FEMA money to Depew

FEMA National Risk Index December 2025 · OpenFEMANatural hazards in Depew →

Climate in Depew

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Depew has chilly, snowy winters and pleasant summers. A typical July afternoon reaches 81°, a January night drops to 18°, and about 95 inches of snow falls in a normal winter.

35° / 20°Winter

56° / 35°Spring

79° / 59°Summer

61° / 43°Fall