Saltillo is a city in Lee County, Mississippi, United States. It is located in the northern part of the Tupelo micropolitan area. Founded in 1849, the population was 4,922 at the 2020 Census.

Official town website ↗

From Wikipedia, licensed CC BY-SA 4.0 · facts via Wikidata (CC0)

How Saltillo ranks

All →

#11Highest income in MS #12Closest to a top hospital in MS #21Fewest uninsured in MS All MS rankings →

Town numbers

ZIP code38866

Area code662

Living in Saltillo

Housing in Saltillo

$245K▲ 5.9% in a year Typical home value · Zillow

The typical Saltillo home is worth about $245,000, up 5.9% in a year, 24% above the Mississippi typical home.

Only 4 sales in May 2026, too few for a market read. The typical value is the steadier guide.

Zillow Home Value Index · Redfin Data CenterHousing market →

Work & commute in Saltillo

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Most working residents leave Saltillo for work: only 3% work in town. The top destinations are Tupelo (47%), Oxford (2%) and Fulton (2%). Half commute less than 10 miles.

Tupelo

47%

Oxford

Fulton

New Albany

3%Work in townlive and work in Saltillo 10 miWhere do people commute?the commute map 1,544Jobs based herea commuter town

Census LEHD 2023 · ACSWork & commute in Saltillo →

Health in Saltillo

C⁺

Health Grade C+

Healthier than 36% of U.S. towns on seven CDC estimates.

Compared with Mississippi

9better than MS

of 32 measures CDC estimates. The other 23 are too close to call.

Conditions 4▲ 8 close Habits all close Care 1▲ 6 close Mind all close Everyday needs 4▲ 0 close

BetterToo close to callWorse

What stands out

13.3%Fewer older adults who have lost all their teethMS 18.5% · better 17.2%Fewer adults facing food insecurityMS 22.4% · better

Care nearby

North Mississippi Medical CenterTupelo · 9.5 mi · ER

Access Family Health Services - TupeloTupelo · 8.9 mi · sliding-scale fees

Primary careShortage · county-wide

DentalShortage · county-wide

Mental healthShortage · county-wide

CDC PLACES 2025 · modeled estimates for adults · CDC's estimate for Saltillo · CMS · HRSAHealth in Saltillo →

Natural hazards in Saltillo

Moderate

Expected storm and flood damage is higher than in 56% of U.S. communities.

🌊 Inland flooding🏚️ Earthquakes🥶 Cold waves

34Does Saltillo flood?paid flood claims since 2004 6Disasters that paid out herefederal disasters sent FEMA money to Saltillo

FEMA National Risk Index December 2025 · OpenFEMANatural hazards in Saltillo →

Climate in Saltillo

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Saltillo has mild winters and warm summers, with plenty of rain. A typical July afternoon reaches 91°, a January night drops to 32°, and snow is almost unheard of.

54° / 34°Winter

74° / 50°Spring

90° / 68°Summer

75° / 51°Fall

How much snow does Saltillo get?Almost none.Rain & snow →When is the first frost?Around Nov 10, with the last in spring around Mar 21.Frost dates →Is it warmer than it used to be?+0.4° vs. the 20th century.Then & now →

NOAA U.S. Climate Normals, 1991–2020Climate in Saltillo →

Schools in Saltillo

All Saltillo schools →

School Grade B

The public schools Saltillo’s kids attend, from kindergarten through graduation, outperform 64% of Mississippi’s districts on state tests and graduation. Among towns with similar incomes, they rank near the bottom.

#27Best public schoolsof 92 in MS

DistrictLee CountySchools3

Saltillo Primary SchoolElementary · Grades PK–2 · 704 students Saltillo Elementary School B+Elementary · Grades 3–5 · 696 students Saltillo High School B+High · Grades 9–13 · 939 students

School data from the U.S. Department of Education (NCES, EDFacts). The School Grade is our own summary of state test results and graduation rates, graded within MS. Ratings are from neighbors.