Maysville is a city in DeKalb County, Missouri, United States. The population was 1,095 at the 2020 census. Maysville is the county seat of DeKalb County. Maysville is part of the St. Joseph, Missouri metropolitan area.

From Wikipedia, licensed CC BY-SA 4.0 · facts via Wikidata (CC0)

Town numbers

ZIP code64469

Area code816

Living in Maysville

Housing in Maysville

$226K▲ 3.1% in a year Typical home value · Zillow

The typical Maysville home is worth about $226,000, up 3.1% in a year, 15% below the Missouri typical home.

Only 2 sales in April 2026, too few for a market read. The typical value is the steadier guide.

Zillow Home Value Index · Redfin Data CenterHousing market →

Work & commute in Maysville

Full picture →

Most working residents leave Maysville for work: only 16% work in town. The top destinations are St. Joseph (16%), Kansas City (9%) and Cameron (8%). Half commute less than 27 miles.

St. Joseph

16%

Kansas City

Cameron

Liberty

16%Work in townlive and work in Maysville 27 miWhere do people commute?the commute map 352Jobs based herea commuter town

Census LEHD 2023 · ACSWork & commute in Maysville →

Health in Maysville

Compared with Missouri

1worse than MO

of 32 measures CDC estimates. The other 31 are too close to call.

Conditions 1▼ 11 close Habits all close Care all close Mind all close Everyday needs all close

BetterToo close to callWorse

What stands out

9.7%More adults who have had cancerMO 8.6% · worse

Care nearby

Cameron Regional Medical CenterCameron · 12.8 mi · ER

King City ClinicKing City · 14.3 mi · sliding-scale fees

Primary careShortage · county-wide

DentalShortage · county-wide

Mental healthShortage · county-wide

CDC PLACES 2025 · modeled estimates for adults · CDC's estimate for Maysville · CMS · HRSAHealth in Maysville →

Natural hazards in Maysville

Moderate

Expected storm and flood damage is higher than in 52% of U.S. communities.

🌊 Inland flooding🌪️ Tornadoes🥶 Cold waves

0Does Maysville flood?no paid flood claims on record 2Disasters that paid out herefederal disasters sent FEMA money to Maysville

FEMA National Risk Index December 2025 · OpenFEMANatural hazards in Maysville →

Climate in Maysville

Full climate →

Maysville has chilly winters and warm summers. A typical July afternoon reaches 88°, a January night drops to 17°, and about 21 inches of snow falls in a normal winter.

39° / 20°Winter

64° / 42°Spring

86° / 64°Summer

66° / 43°Fall