Middletown is a city in Des Moines County, Iowa, United States. The population was 363 at the time of the 2020 census. It is part of the Burlington, IA–IL Micropolitan Statistical Area.

From Wikipedia, licensed CC BY-SA 4.0 · facts via Wikidata (CC0)

Town numbers

ZIP code52638

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Living in Middletown

Housing in Middletown

$187K▲ 7.1% in a year Typical home value · Zillow

The typical Middletown home is worth about $187,000, up 7.1% in a year, 22% below the Iowa typical home.

Zillow Home Value Index · Redfin Data CenterHousing market →

Work & commute in Middletown

Full picture →

Most working residents leave Middletown for work: only 2% work in town. The top destinations are Burlington (25%), West Burlington (13%) and Mount Pleasant (7%). Half commute less than 14 miles.

Burlington

25%

West Burlington

13%

Mount Pleasant

Fort Madison

2%Work in townlive and work in Middletown 14 miWhere do people commute?the commute map 666Jobs based herea job hub

Census LEHD 2023 · ACSWork & commute in Middletown →

Health in Middletown

Compared with Iowa

1better than IA

of 32 measures CDC estimates. The other 31 are too close to call.

Conditions 1▲ 11 close Habits all close Care all close Mind all close Everyday needs all close

BetterToo close to callWorse

What stands out

9.1%Fewer older adults who have lost all their teethIA 11.6% · better

Care nearby

Southeast Iowa Regional Medical CenterWest Burlington · 5 mi · ER

Chc/Seia West Burlington ClinicWest Burlington · 4.6 mi · sliding-scale fees

Primary careShortage · county-wide

DentalShortage · county-wide

Mental healthShortage · county-wide

CDC PLACES 2025 · modeled estimates for adults · CDC's estimate for Middletown · CMS · HRSAHealth in Middletown →

Natural hazards in Middletown

Moderate

Expected storm and flood damage is higher than in 45% of U.S. communities.

🌊 Inland flooding🌵 Drought🌪️ Tornadoes

0Does Middletown flood?no paid flood claims on record NoneDisasters that paid out hereof 24 declared for Des Moines County

FEMA National Risk Index December 2025 · OpenFEMANatural hazards in Middletown →

Climate in Middletown

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Middletown has chilly winters and warm summers. A typical July afternoon reaches 85°, a January night drops to 16°, and about 22 inches of snow falls in a normal winter.

35° / 19°Winter

62° / 41°Spring

84° / 63°Summer

64° / 43°Fall