Town guide
Greenville
Missouri · MO
About Greenville
City in Missouri, U.S.443Population
0.7 sq miArea
407 ftElevation
Greenville is a city in and the county seat of Wayne County, Missouri, United States, that is located on U.S. Route 67 near the intersection with Route D and E along the St. Francis River. The population was 443 at the 2020 census. Greenville was incorporated and founded as the county seat of Wayne County in 1819.
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